The role of biomarkers as a diagnostic tool in some neoplasms of pet animals

Authors

  • Abdelmoneim A. Ali Pathology Department, Faculty of Veterinary Medicine, Zagazig University, Sharkia, Zagazig 44159, Egypt.
  • Nahla A.G. Ahmed Refat Pathology Department, Faculty of Veterinary Medicine, Zagazig University, Sharkia, Zagazig 44159, Egypt.
  • Mohamed M.M. Metwally Pathology Department, Faculty of Veterinary Medicine, Zagazig University, Sharkia, Zagazig 44159, Egypt.
  • Ashraf M. Fathi Department of Pathology, Animal Health Research Institute (AHRI), Agricultural Research Center (ARC), Cairo, Egypt.
  • Mohammed S. Sobh Pathology Department, Faculty of Veterinary Medicine, Zagazig University, Sharkia, Zagazig 44159, Egypt.

Keywords:

Egypt , Neoplasms , Pets , Histopathology , Immunohistochemistry

Abstract

Cancerous tumors are one of the main problems that cause of deaths in pet animals. The objective of this paper is to describe histopathological features of some neoplastic masses with confirmation using immunohistochemistry in pet animals.  Our study was done from May 2022 to August 2023 in Sharkia governorate, Egypt to correctly recognize 7 cases of pet animal neoplasms "5 cases of dogs and 2 queen case" based on histopathological and immunohistochemical findings.  The results revealed 2 cases of TVT in Penis with positive expressions for Iba2 and vimentin  , 1 Case of Sebaceous adenoma in Hock joint of male dog skin, 1 case of hepatoid carcinoma in perianal glands of male dog with positive immunolabelling for CK7  , 1 case of chondroblastic osteosarcoma  in A 4-year old, male, Great Dane dog  and 2 cases of queen with mammary gland adenocarcinoma with positive immunoreactivity for HER-2 and other mixed mammary neoplasm accompanied with sarcoma has positive staining for vimentin. It could be concluded that  the histopathological evaluations by H&E stain is the backbone method for neoplasms diagnosis and  using some  biomarkers added a confirmatory tools for these diagnosis.

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Published

2024-03-03

How to Cite

Ali, A. A. ., Refat, N. A. A. ., Metwally, M. M. ., Fathi, A. M. ., & Sobh, M. S. . (2024). The role of biomarkers as a diagnostic tool in some neoplasms of pet animals . Journal of Advanced Veterinary Research, 14(3), 505-509. Retrieved from https://www.advetresearch.com/index.php/AVR/article/view/1704

Issue

Vol. 14 No. 3 (2024): Special Issue: The 18th Scientific Conference, Faculty of Veterinary Medicine, Zagazig University (Veterinary Medicine and One Health in Light of Climate Changes)

Section

Original Research

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